Professor of Biology; PhD, University of Iowa
Dr. Yuan C. Lee graduated from National Taiwan Univ. (Agri. Chem) and obtained a PhD (Biochemistry) at Univ. of Iowa (Iowa City). After 3-yr postdoctoral training at Biochem. Dept. (under Prof. Clinton E. Ballou, he joined the Biology Dept. of Johns Hopkins Univ., as an Assistant Professor (1965). After Assist. Prof (1970), he became a Prof (2014-20). He joined the Academy in 2021. Although his main interest is in Glycobiology, especially disease-related problems. he promoted synthetic glycoproteins, coined “Neoglycoproteins”, through which he discovered the “Glycoside-clustering effect”. For example, mammalian hepatocytes bind tri-branched Galactose terminal 103-fold stronger than a single galactose.
Current Interests: PATHOGEN-targeting oligosaccharide derivatives